2022 

Gecse K, Édes AE, Nagy T, Demeter AK, Virág D, Király M, Dalmadi Kiss B, Ludányi K, Környei Z, Denes A, Bagdy G, Juhasz G. Citalopram Neuroendocrine Challenge Shows Altered Tryptophan and Kynurenine Metabolism in Migraine. Cells. 2022;11(14):2258.

 

Gecse K, Dobos D, Aranyi CS, Galambos A, Baksa D, Kocsel N, Szabó E, Pap D, Virág D, Ludányi K, Kökönyei G, Emri M, Bagdy G, Juhasz G. Association of plasma tryptophan concentration with periaqueductal gray matter functional connectivity in migraine patients. Sci Rep. 2022;12(1):739.

 

Ujma PP, Eszlári N, Millinghoffer A, Bruncsics B, Török D, Petschner P, Antal P, Deakin B, Breen G, Bagdy G, Juhász G. Genetic effects on educational attainment in Hungary. Brain Behav. 2022 (1):e2430.

 

Baksa D, Szabo E, Kocsel N, Galambos A, Edes AE, Pap D, Zsombok T, Magyar M, Gecse K, Dobos D, Kozak LR, Bagdy G, Kokonyei G, Juhasz G. Circadian Variation of Migraine Attack Onset Affects fMRI Brain Response to Fearful Faces. Front Hum Neurosci. 2022;16:842426.

 

Mahdi M, Hermán L, Réthelyi JM, Bálint BL. Potential Role of the Antidepressants Fluoxetine and Fluvoxamine in the Treatment of COVID-19. Int J Mol Sci. 2022;23(7):3812.

 

Jdeed S, Erdős E, Bálint BL, Uray IP. The Role of ARID1A in the Nonestrogenic Modulation of IGF-1 Signaling. Mol Cancer Res. 2022;20(7):1071-1082.

 

Szűcs, Z.; Pinti, É.; Haltrich, I.; Szén, O.P.; Nagy, T.; Barta, E.; Méhes, G.; Bidiga, L.; Török, O.; Ujfalusi, A.; Koczok, K.; Balogh, I. An Ultra-Rare Manifestation of an X-Linked Recessive Disorder: Duchenne Muscular Dystrophy in a Female Patient. Int. J. Mol. Sci. 2022, 23, 13076.

 

Szűcs, Z.; Pinti, É.; Haltrich, I.; Szén, O.P.; Nagy, T.; Barta, E.; Méhes, G.; Bidiga, L.; Török, O.; Ujfalusi, A.; Koczok, K.; Balogh, I. An Ultra-Rare Manifestation of an X-Linked Recessive Disorder: Duchenne Muscular Dystrophy in a Female Patient. Int. J. Mol. Sci. 2022, 23, 13076.

 

Sramkó G, Kosztolányi A, Laczkó L, Rácz R, Szatmári L, Varga Z, Barta Z. Range-wide phylogeography of the flightless steppe beetle Lethrus apterus (Geotrupidae) reveals recent arrival to the Pontic Steppes from the west. Sci Rep. 2022 Mar 24;12(1):5069.

 

Fülöp A, Németh Z, Kocsis B, Deák-Molnár B, Bozsoky T, Csöppü G, Barta Z. 2022. Fighting ability, personality and melanin signalling in free-living Eurasian tree sparrows (Passer montanus) PeerJ 10:e13660

 

Bán, M., Boné, G.M., Bérces, S. Barta Z. et al. OpenBioMaps – self-hosted data management platform and distributed service for biodiversity related data. Earth Sci Inform 15, 2007–2016 (2022).

 

M. Miklós, L. Laczkó,G. Sramkó, Z. Barta, J.Tökölyi Seasonal variation of genotypes and reproductive plasticity in a facultative clonal freshwater invertebrate animal (Hydra oligactis) living in a temperate lake, Ecology and Evolution, 2022

 

Bartha Á, Győrffy B. TNMplot.com: A Web Tool for the Comparison of Gene Expression in Normal, Tumor and Metastatic Tissues. Int J Mol Sci. 2021;22(5):2622

 

Kotmayer L, Romero-Moya D, Marin-Bejar O, Kozyra E, Català A, Bigas A, Wlodarski MW, Bödör C, Giorgetti A. GATA2 deficiency and MDS/AML: Experimental strategies for disease modelling and future therapeutic prospects. Br J Haematol. 2022;199(4):482-495.

 

Dreyling M, André M, Gökbuget N, Tilly H, Jerkeman M, Gribben J, Ferreri A, Morel P, Stilgenbauer S, Fox C, Ribera JM., Bödör C.  The EHA research roadmap: malignant lymphoid diseases. HemaSphere. 2022;6(6):e726.

 

Karvaly, G.B.; Vincze, I.; Balogh, A.; Köllő, Z.; Bödör, C.; Vásárhelyi, B. A High-Throughput Clinical Laboratory Methodology for the Therapeutic Monitoring of Ibrutinib and Dihydrodiol Ibrutinib. Molecules 2022, 27, 4766.

 

Armes H, Rio-Machin A, Krizsán S, Bödör C, Kaya F, Bewicke-Copley F, Alnajar J, Walne A, Péterffy B, Tummala H, Rouault-Pierre K, Dokal I, Vulliamy T, Fitzgibbon J. Acquired somatic variants in inherited myeloid malignancies. Leukemia. 2022;36(5):1377-1381.

 

Gángó A, Kiss R, Farkas P, Hanna E, Demeter J, Deák B, Lévai D, Kotmayer L, Alpár D, Matolcsy A, Bödör C, Mátrai Z, Timár B. Morphologic and molecular analysis of Richter syndrome in chronic lymphocytic leukaemia patients treated with ibrutinib or venetoclax. Pathology. 2022;54(1):95-103.

 

Bedics G, Kotmayer L, Zajta E, Hegyi LL, Brückner EÁ, Rajnai H, Reiniger L, Bödör C, Garami M, Scheich B. Germline MUTYH mutations and high-grade gliomas: Novel evidence for a potential association. Genes Chromosomes Cancer. 2022;61(10):622-628.

 

Sebestyén E, Nagy Á, Marosvári D, Rajnai H, Kajtár B, Deák B, Matolcsy A, Brandner S, Storhoff J, Chen N, Bagó AG, Bödör C, Reiniger L. Distinct miRNA Expression Signatures of Primary and Secondary Central Nervous System Lymphomas. J Mol Diagn. 2022;24(3):224-240.

 

Jenei A, Bedics G, Erdélyi DJ, Müller J, Györke T, Bödör C, Szepesi Á. Potential role of MAP2K1 mutation in the trans-differentiation of interdigitating dendritic cell sarcoma: Case report and literature review. Front Pediatr. 2022 Sep 16;10:959307.

 

Nagy ZF, Ferenczi K, Istenes I, Eid H, Bödör C, Timár B, Demeter J. Case Report: Development of Diffuse Large B Cell Lymphoma a Long Time After Hairy Cell Leukemia. Pathol Oncol Res. 2022 Apr 29;28:1610338.

 

Jákob N, Pintér GT, Kotmayer L, Nagy P, Bödör C, Barabás P, Bécser J, Szabó G, Bogdán S. A cherubismus előfordulása három testvérben [Cherubism in three siblings]. Orv Hetil. 2022 Mar 13;163(11):446-452. Hungarian.

 

Szekely T, Krenacs T, Maros ME, Bodor C, Daubner V, Csizmadia A, Vrabely B, Timar B. Correlations Between the Expression of Stromal Cell Activation Related Biomarkers, L-NGFR, Phospho-ERK1-2 and CXCL12, and Primary Myelofibrosis Progression. Pathol Oncol Res. 2022 Mar 14;28:1610217.

 

Mentes A, Papp K, Visontai D, Stéger J; VEO Technical Working Group, Csabai I, Medgyes-Horváth A, Pipek OA. Identification of mutations in SARS-CoV-2 PCR primer regions. Sci Rep. 2022 Nov 4;12(1):18651.

 

Pataki BÁ, Olar A, Ribli D, Pesti A, Kontsek E, Gyöngyösi B, Bilecz Á, Kovács T, Kovács KA, Kramer Z, Kiss A, Szócska M, Pollner P, Csabai I. HunCRC: annotated pathological slides to enhance deep learning applications in colorectal cancer screening. Sci Data. 2022;9(1):370.

 

Zsigrai S, Kalmár A, Barták BK, Nagy ZB, Szigeti KA, Valcz G, Kothalawala W, Dankó T, Sebestyén A, Barna G, Pipek O, Csabai I, Tulassay Z, Igaz P, Takács I, Molnár B. Folic Acid Treatment Directly Influences the Genetic and Epigenetic Regulation along with the Associated Cellular Maintenance Processes of HT-29 and SW480 Colorectal Cancer Cell Lines. Cancers (Basel). 2022;14(7):1820.

 

Gokuldass A, Schina A, Lauss M, Harbst K, Chamberlain CA, Draghi A, Westergaard MCW, Nielsen M, Papp K, Sztupinszki Z, Csabai I, Svane IM, Szallasi Z, Jönsson G, Donia M. Transcriptomic signatures of tumors undergoing T cell attack. Cancer Immunol Immunother. 2022;71(3):553-563.

 

Zrubka Z, Csabai I, Hermann Z, Golicki D, Prevolnik-Rupel V, Ogorevc M, Gulácsi L, Péntek M. Predicting Patient-Level 3-Level Version of EQ-5D Index Scores From a Large International Database Using Machine Learning and Regression Methods. Value Health. 2022 Sep;25(9):1590-1601.

 

Reguly IZ, Csercsik D, Juhász J, Tornai K, Bujtár Z, Horváth G, Keömley-Horváth B, Kós T, Cserey G, Iván K, Pongor S, Szederkényi G, Röst G, Csikász-Nagy A. Microsimulation based quantitative analysis of COVID-19 management strategies. PLoS Comput Biol. 2022 ;18(1): e1009693.

 

Miski M, Keömley-Horváth BM, Rákóczi Megyeriné D, Csikász-Nagy A, Gáspári Z. Diversity of synaptic protein complexes as a function of the abundance of their constituent proteins: A modeling approach. PLoS Comput Biol. 2022;18(1):e1009758.

 

Guba A, Bába O, Tőzsér J, Csősz É, Kalló G. Fast and Sensitive Quantification of AccQ-Tag Derivatized Amino Acids and Biogenic Amines by UHPLC-UV Analysis from Complex Biological Samples. Metabolites. 2022;12(3):272.

 

Lénárt K, Bankó C, Ujlaki G, Póliska S, Kis G, Csősz É, Antal M, Bacso Z, Bai P, Fésüs L, Mádi A. Tissue Transglutaminase Knock-Out Preadipocytes and Beige Cells of Epididymal Fat Origin Possess Decreased Mitochondrial Functions Required for Thermogenesis. Int J Mol Sci. 2022;23(9):5175.

 

Kalló G, Kumar A, Tőzsér J, Csősz É. Chemical Barrier Proteins in Human Body Fluids. Biomedicines. 2022;10(7):1472.

 

Nokhoijav E, Guba A, Kumar A, Kunkli B, Kalló G, Káplár M, Somodi S, Garai I, Csutak A, Tóth N, Emri M, Tőzsér J, Csősz É. Metabolomic Analysis of Serum and Tear Samples from Patients with Obesity and Type 2 Diabetes Mellitus. Int J Mol Sci. 2022;23(9):4534.

 

Czegledi L, Csosz E, Gulyas G. Relationship between Plasma Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Level and Proteome Profile of Cows. Animals (Basel). 2022 Jun 16;12(12):1559.

 

Szaniszló T, Fülöp M, Pajkos M, Erdős G, Kovács RÁ, Vadászi H, Kardos J, Dosztányi Z. The interaction between LC8 and LCA5 reveals a novel oligomerization function of LC8 in the ciliary-centrosome system. Sci Rep. 2022;12(1):15623.

 

Kastano K, Mier P, Dosztányi Z, Promponas VJ, Andrade-Navarro MA. Functional Tuning of Intrinsically Disordered Regions in Human Proteins by Composition Bias. Biomolecules. 2022;12(10):1486.

 

Quaglia F, Mészáros B, Tsirigos KD, Veljkovic N, Parisi G, Ventura S, Dosztányi Z, Tompa P, Tosatto SCE, Piovesan D. et al. DisProt in 2022: improved quality and accessibility of protein intrinsic disorder annotation. Nucleic Acids Res. 2022 Jan 7;50(D1):D480-D487.

 

Miski M, Keömley-Horváth BM, Rákóczi Megyeriné D, Csikász-Nagy A, Gáspári Z. Diversity of synaptic protein complexes as a function of the abundance of their constituent proteins: A modeling approach. PLoS Comput Biol. 2022;18(1):e1009758.

 

Dürvanger Z, Boros E, Nagy ZA, Hegedüs R, Megyeri M, Dobó J, Gál P, Schlosser G, Ángyán AF, Gáspári Z, Perczel A, Harmat V, Mező G, Menyhárd DK, Pál G. Directed Evolution-Driven Increase of Structural Plasticity Is a Prerequisite for Binding the Complement Lectin Pathway Blocking MASP-Inhibitor Peptides. ACS Chem Biol. 2022;17(4):969-986.

 

Kalman ZE, Dudola D, Mészáros B, Gáspári Z, Dobson L. PSINDB: the postsynaptic protein-protein interaction database. Database (Oxford). 2022; (2022):baac007.

 

Szabó AL, Sánta A, Pancsa R, Gáspári Z. Charged sequence motifs increase the hpropensity towards liquid-liquid phase separation. FEBS Lett. 2022;596(8):1013-1028.

 

Sánta A, Czajlik A, Batta G, Péterfia B, Gáspári Z. Resonance assignment of the Shank1 PDZ domain. Biomol NMR Assign. 2022;16(1):121-127.

 

Felső R, Lányi É, Erhardt É, Laufer Z, Kardos D, Herczeg R, Gyenesei A, Hollódy K, Molnár D. Total sleep deprivation decreases saliva ghrelin levels in adolescents. J Sleep Res. 2022 Oct 11:e13746.

 

Aczél T, Benczik B, Ágg B, Körtési T, Urbán P, Bauer W, Gyenesei A, Tuka B, Tajti J, Ferdinandy P, Vécsei L, Bölcskei K, Kun J, Helyes Z. Disease- and headache-specific microRNA signatures and their predicted mRNA targets in peripheral blood mononuclear cells in migraineurs: role of inflammatory signalling and oxidative stress. J Headache Pain. 2022 Sep 2;23(1):113.

 

Pohóczky K, Kun J, Szentes N, Aczél T, Urbán P, Gyenesei A, Bölcskei K, Szőke É, Sensi S, Dénes Á, Goebel A, Tékus V, Helyes Z. Discovery of novel targets in a complex regional pain syndrome mouse model by transcriptomics: TNF and JAK-STAT pathways. Pharmacol Res. 2022 Aug;182:106347.

 

Tompa M, Kraboth Z, Galik B, Kajtar B, Gyenesei A, Kalman B. Epigenetic Suppression of the IL-7 Pathway in Progressive Glioblastoma. Biomedicines. 2022;10(9):2174.

 

Jia X, Bene J, Balázs N, Szabó K, Berta G, Herczeg R, Gyenesei A, Balogh P. Age-Associated B Cell Features of the Murine High-Grade B Cell Lymphoma Bc.DLFL1 and Its Extranodal Expansion in Abdominal Adipose Tissues. J Immunol. 2022 Jun 15;208(12):2866-2876.

 

Mutuku C, Melegh S, Kovacs K, Urban P, Virág E, Heninger R, Herczeg R, Sonnevend Á, Gyenesei A, Fekete C, Gazdag Z. Characterization of β-Lactamases and Multidrug Resistance Mechanisms in Enterobacterales from Hospital Effluents and Wastewater Treatment Plant. Antibiotics (Basel). 2022 Jun 7;11(6):776.

 

Takács-Lovász K, Kun J, Aczél T, Urbán P, Gyenesei A, Bölcskei K, Szőke É, Helyes Z. PACAP-38 Induces Transcriptomic Changes in Rat Trigeminal Ganglion Cells Related to Neuroinflammation and Altered Mitochondrial Function Presumably via PAC1/VPAC2 Receptor-Independent Mechanism. Int J Mol Sci. 2022 Feb 14;23(4):2120.

 

Hegyi ÁI, Otto M, Geml J, Hegyi-Kaló J, Kun J, Gyenesei A, Pierneef R, Váczy KZ. Metatranscriptomic Analyses Reveal the Functional Role of Botrytis cinerea in Biochemical and Textural Changes during Noble Rot of Grapevines. J Fungi (Basel). 2022 Apr 8;8(4):378.

 

Pham D, Polgar B, Toth T, Jungling A, Kovacs N, Balas I, Pal E, Szabo D, Fulop BD, Reglodi D, Szanto Z, Herczeg R, Gyenesei A, Tamas A. Examination of pituitary adenylate cyclase-activating polypeptide in Parkinson's disease focusing on correlations with motor symptoms. Geroscience. 2022 Apr;44(2):785-803.

 

Maasz A, Hadzsiev K, Ripszam R, Zsigmond A, Maka E, Knezy K, Lesch B, Nemeth A, Bene J, Galik B, Gyenesei A, Melegh B. TUBB4B gene mutation in Leber phenotype of congenital amaurosis syndrome associated with early-onset deafness. Eur J Med Genet. 2022;65(4):104471.

 

Gervain J, Szabóné Bartha K, Bakiné Hodovánszky E, Kadlecsik L, Herczeg R, Gyenesei A, Simon J. Az anti-SARS-CoV-2-IgG-antitest-immunválaszok monitorozása magyarországi egészségügyi dolgozók két kohorszában fertőzést, illetve immunizálást követően [Monitoring of anti-SARS-CoV-2 IgG antibody immune responses in two cohorts of Hungarian healthcare workers following infection or immunization]. Orv Hetil. 2022 Mar 20;163(12):455-462. Hungarian

 

Harrod A, Lai CF, Goldsbrough I, Simmons GM, Oppermans N, Santos DB, Győrffy B, Allsopp RC, Toghill BJ, Balachandran K, Lawson M, Morrow CJ, Surakala M, Carnevalli LS, Zhang P, Guttery DS, Shaw JA, Coombes RC, Buluwela L, Ali S. Genome engineering for estrogen receptor mutations reveals differential responses to anti-estrogens and new prognostic gene signatures for breast cancer. Oncogene. 2022;41(44):4905-4915.

 

Ding X, Sharko AC, McDermott MSJ, Schools GP, Chumanevich A, Ji H, Li J, Zhang L, Mack ZT, Sikirzhytski V, Shtutman M, Ivers L, O'Donovan N, Crown J, Győrffy B, Chen M, Roninson IB, Broude EV. Inhibition of CDK8/19 Mediator kinase potentiates HER2-targeting drugs and bypasses resistance to these agents in vitro and in vivo. Proc Natl Acad Sci U S A. 2022 ;119(32):e2201073119.

 

Kahl I, Mense J, Finke C, Boller AL, Lorber C, Győrffy B, Greve B, Götte M, Espinoza-Sánchez NA. The cell cycle-related genes RHAMM, AURKA, TPX2, PLK1, and PLK4 are associated with the poor prognosis of breast cancer patients. J Cell Biochem. 2022 Mar;123(3):581-600.

 

Ladányi A, Rásó E, Barbai T, Vízkeleti L, Puskás LG, Kovács SA, Győrffy B, Tímár J. Identification of a Tumor Cell Associated Type I IFN Resistance Gene Expression Signature of Human Melanoma, the Components of Which Have a Predictive Potential for Immunotherapy. Int J Mol Sci. 2022 Feb 28;23(5):2704.

 

Munkácsy G, Herman P, Győrffy B. Comparison of scientometric achievements at PhD and scientific output ten years later for 4,790 academic researchers. PLoS One. 2022 Jul 27;17(7):e0271218.

 

Munkácsy G, Santarpia L, Győrffy B. Gene Expression Profiling in Early Breast Cancer-Patient Stratification Based on Molecular and Tumor Microenvironment Features. Biomedicines. 2022 Jan 24;10(2):248.

 

Kovács SA, Győrffy B. Transcriptomic datasets of cancer patients treated with immune-checkpoint inhibitors: a systematic review. J Transl Med. 2022;20(1):249.

 

Olah C, Reis H, Hoffmann MJ, Mairinger F, Ting S, Hadaschik B, Krafft U, Grünwald V, Nyirady P, Varadi M, Győrffy B, Kiss A, Szekely E, Sjödahl G, Szarvas T. Predictive value of molecular subtypes and APOBEC3G for adjuvant chemotherapy in urothelial bladder cancer. Cancer Med. 2022.

 

Viganò L, Locatelli A, Ulisse A, Galbardi B, Dugo M, Tosi D, Tacchetti C, Daniele T, Győrffy B, Sica L, Macchini M, Zambetti M, Zambelli S, Bianchini G, Gianni L. Modulation of the Estrogen/erbB2 Receptors Cross-talk by CDK4/6 Inhibition Triggers Sustained Senescence in Estrogen Receptor- and ErbB2-positive Breast Cancer. Clin Cancer Res. 2022;28(10):2167-2179.

 

Hegedüs L, Livingstone E, Bánkfalvi Á, Viehof J, Enyedi Á, Bilecz Á, Győrffy B, Baranyi M, Tőkés AM, Gil J, Marko-Varga G, Griewank KG, Zimmer L, Váraljai R, Sucker A, Zaremba A, Schadendorf D, Aigner C, Hegedüs B. The Prognostic Relevance of PMCA4 Expression in Melanoma: Gender Specificity and Implications for Immune Checkpoint Inhibition. Int J Mol Sci. 2022;23(6):3324.

 

Tibor Fekete J, Győrffy B. A unified platform enabling biomarker ranking and validation for 1562 drugs using transcriptomic data of 1250 cancer cell lines. Comput Struct Biotechnol J. 2022 Jun 6;20:2885-2894.

 

Mazzeschi M, Sgarzi M, Romaniello D, Gelfo V, Cavallo C, Ambrosi F, Morselli A, Miano C, Laprovitera N, Girone C, Ferracin M, Santi S, Rihawi K, Ardizzoni A, Fiorentino M, D'Uva G, Győrffy B, Palmer R, Lauriola M. The autocrine loop of ALK receptor and ALKAL2 ligand is an actionable target in consensus molecular subtype 1 colon cancer. J Exp Clin Cancer Res. 2022;41(1):113.

 

Ágoston EI, Acs B, Herold Z, Fekete K, Kulka J, Nagy A, Mühl D, Mohacsi R, Dank M, Garay T, Harsanyi L, Győrffy B, Szasz AM. Deconstructing Immune Cell Infiltration in Human Colorectal Cancer: A Systematic Spatiotemporal Evaluation. Genes (Basel). 2022;13(4):589.

 

Dmello C, Sonabend A, Arrieta VA, Zhang DY, Kanojia D, Chen L, Gould A, Zhang J, Kang SJ, Winter J, Horbinski C, Amidei C, Győrffy B, Cordero A, Chang CL, Castro B, Hsu P, Ahmed AU, Lesniak MS, Stupp R, Sonabend AM. Translocon-associated Protein Subunit SSR3 Determines and Predicts Susceptibility to Paclitaxel in Breast Cancer and Glioblastoma. Clin Cancer Res. 2022;28(14):3156-3169.

 

Müller D, Győrffy B. DNA methylation-based diagnostic, prognostic, and predictive biomarkers in colorectal cancer. Biochim Biophys Acta Rev Cancer. 2022;1877(3):188722

 

Riecks J, Parnigoni A, Győrffy B, Kiesel L, Passi A, Vigetti D, Götte M. The hyaluronan-related genes HAS2, HYAL1-4, PH20 and HYALP1 are associated with prognosis, cell viability and spheroid formation capacity in ovarian cancer. J Cancer Res Clin Oncol. 2022;148(12):3399-3419.

 

Pai P, Wang G, Teo WW, Raez-Rodriguez D, Gabrielson KL, Győrffy B, Downs BM, Aggarwal A, Sukumar S. HOXA5-Mediated Stabilization of IκBα Inhibits the NF-κB Pathway and Suppresses Malignant Transformation of Breast Epithelial Cells. Cancer Res. 2022 ;82(20):3802-3814.

 

Pálinkás HL, Pongor L, Balajti M, Nagy Á, Nagy K, Békési A, Bianchini G, Vértessy BG, Győrffy B. Primary Founder Mutations in the PRKDC Gene Increase Tumor Mutation Load in Colorectal Cancer. Int J Mol Sci. 2022;23(2):633.

 

Regan JL, Schumacher D, Staudte S, Steffen A, Lesche R, Toedling J, Jourdan T, Haybaeck J, Golob-Schwarzl N, Mumberg D, Henderson D, Győrffy B, Regenbrecht CRA, Keilholz U, Schäfer R, Lange M. Identification of a neural development gene expression signature in colon cancer stem cells reveals a role for EGR2 in tumorigenesis. iScience. 2022; 25(7):104498.

 

Palassin P, Lapierre M, Bonnet S, Pillaire MJ, Győrffy B, Teyssier C, Jalaguier S, Hoffmann JS, Cavaillès V, Castet-Nicolas A. RIP140 regulates POLK gene expression and the response to alkylating drugs in colon cancer cells. Cancer Drug Resist. 2022;5(2):401-414.

 

Alcaraz-Sanabria A, Cabañas Morafraile E, Fernández-Hinojal G, Velasco G, Pérez-Segura P, Pandiella A, Győrffy B, Ocaña A. Transcriptomic Mapping of Non-Small Cell Lung Cancer K-RAS p.G12C Mutated Tumors: Identification of Surfaceome Targets and Immunologic Correlates. Front Immunol. 2022;12:786069.

 

Olah C, Hahnen C, Nagy N, Musial J, Varadi M, Nyiro G, Gyorffy B, Hadaschik B, Rawitzer J, Ting S, Sjödahl G, Hoffmann MJ, Reis H, Szarvas T. A quantitative polymerase chain reaction based method for molecular subtype classification of urinary bladder cancer-Stromal gene expressions show higher prognostic values than intrinsic tumor genes. Int J Cancer. 2022;150(5):856-867.

 

Kothalawala WJ, Győrffy B. Transcriptomic and cellular content analysis of colorectal cancer by combining multiple independent cohorts. Clin Transl Gastroenterol. 2022.

 

Benkő M, Aoki K, Arnberg N, Davison AJ, Echavarría M, Hess M, Jones MS, Kaján GL, Kajon AE, Mittal SK, Podgorski II, San Martín C, Wadell G, Watanabe H, Harrach B, Ictv Report Consortium. ICTV Virus Taxonomy Profile: Adenoviridae 2022. J Gen Virol. 2022 ;103(3):001721.g

 

Harrach B, Megyeri A, Papp T, Ursu K, Boldogh SA, Kaján GL. A screening of wild bird samples enhances our knowledge about the biodiversity of avian adenoviruses. Vet Res Commun. 2022

 

Vidovszky MZ, Böszörményi KP, Surján A, Varga T, Dán Á, Benkő M, Harrach B. First DNA sequence proof for the occurrence of bovine adenovirus types 10 and 11 in continental Europe. Transbound Emerg Dis. 2022;

 

Kraberger S, Oswald SA, Arnold JM, Schmidlin K, Custer JM, Levi G, Benkő M, Harrach B, Varsani A. Novel adenovirus associated with common tern (Sterna hirundo) chicks. Arch Virol. 2022;167:659–663.

 

Dastjerdi A, Jeckel S, Davies H, Irving J, Longue C, Plummer C, Vidovszky MZ, Harrach B, Chantrey J, Martineau H, et al. Novel adenovirus associated with necrotizing bronchiolitis in a captive reindeer (Rangifer tarandus). Transbound Emerg Dis. 2022;69:3097–3102.

 

Zadravec M, Račnik J, Slavec B, Ballmann MZ, Kaján GL, Doszpoly A, Zorman-Rojs O, Marhold C, Harrach B. Novel adenoviruses from captive psittacine birds in Slovenia. Comp Immunol Microbiol Infect Dis. 2022;90–91:101902.

 

Gellért Á, Benkő M, Harrach B, Peters M, Kaján GL. The genome and phylogenetic analyses of tit siadenoviruses reveal both a novel avian host and viral species. Infect Genet Evol. 2022;103:105326.

 

Wéber A, Szatmári I, Dobozi M, Hilbert L, Branyiczkiné Géczy G, Nagy P, Kásler M, Polgár C, Kenessey I. A Központi Statisztikai Hivatal halálozási adatainak összevetése a Nemzeti Rákregiszter adatbázisával. Orv Hetil. 2022;163:1481–1489.

 

Borbély K, Emri M, Kenessey I, Tóth M, Singer J, Barsi P, Vajda Z, Pál E, Tóth Z, Beyer T, et al. PET/MRI in the Presurgical Evaluation of Patients with Epilepsy: A Concordance Analysis. Biomedicines. 2022;10:949.

 

Borsodi K, Balla H, Molnár PJ, Lénárt Á, Kenessey I, Horváth A, Keszthelyi A, Romics M, Majoros A, Nyirády P, et al. Signaling Pathways Mediating Bradykinin-Induced Contraction in Murine and Human Detrusor Muscle. Front Med (Lausanne). 2021;8:745638.

 

Farkas G, Kocsis ZS, Székely G, Kenessey I, Polgár C, Jurányi Z. Spontaneous Chromosomal Aberrations in Lymphocytes and Development of Tumor in Hospital Workers. Anticancer Res. 2022;42:1059–1064.

 

Kenessey I, Nagy P, Polgár C. [The Hungarian situation of cancer epidemiology in the second decade of the 21st century]. Magy Onkol. 2022;66:175–184.

 

Bashir F, Kovács S, Ábrahám Á, Nagy K, Ayaydin F, Valkony-Kelemen I, Ferenc G, Galajda P, Tóth SZ, Sass L, Kós PB, Vass I, Szabó M. Viable protoplast formation of the coral endosymbiont alga Symbiodinium spp. in a microfluidics platform. Lab Chip. 2022 ;22(16):2986-2999.

 

Menyhart O, Weltz B, Győrffy B. Correction: MultipleTesting.com: A tool for life science researchers for multiple hypothesis testing correction. PLoS One. 2022;17(9):e0274662.

 

Fekete F, Mangó K, Minus A, Tóth K, Monostory K. CYP1A2 mRNA Expression Rather than Genetic Variants Indicate Hepatic CYP1A2 Activity. Pharmaceutics. 2022;14:532.

 

Mangó K, Kiss ÁF, Fekete F, Erdős R, Monostory K. CYP2B6 allelic variants and non-genetic factors influence CYP2B6 enzyme function. Sci Rep. 2022;12:2984.

 

Nagy I, Baráth BR, Mangó K, Shemirani A-H, Monostory K, Nemes B. The Prognostic Role of CYP Enzyme in Kidney Transplantation: A Single Centre Experience. Transplant Proc. 2022;S0041-1345(22)00716-3.

 

Bányai L, Trexler M, Patthy L. Use of Publication Dynamics to Distinguish Cancer Genes and Bystander Genes. Genes (Basel). 2022 Jun 21;13(7):1105.

 

Reguly IZ, Csercsik D, Juhász J, Tornai K, Bujtár Z, Horváth G, Keömley-Horváth B, Kós T, Cserey G, Iván K, Pongor S, Szederkényi G, Röst G, Csikász-Nagy A. Microsimulation based quantitative analysis of COVID-19 management strategies. PLoS Comput Biol. 2022;18(1):e1009693.

 

Simon I, Magyar C. Assortment of Frontiers in Protein Science. Int J Mol Sci. 2022 ;23(7):3685.

 

Than NG, Posta M, Györffy D, Orosz L, Orosz G, Rossi SW, Ambrus-Aikelin G, Szilágyi A, Nagy S, Hupuczi P, et al. Early pathways, biomarkers, and four distinct molecular subclasses of preeclampsia: The intersection of clinical, pathological, and high-dimensional biology studies. Placenta. 2022;125:10–19.

 

Than NG, Romero R, Györffy D, Posta M, Bhatti G, Done B, Chaemsaithong P, Jung E, Suksai M, Gotsch F, et al. Molecular subclasses of preeclampsia characterized by a longitudinal maternal proteomics study: distinct biomarkers, disease pathways and options for prevention. J Perinat Med. 2022;

 

Erez O, Gotsch F, Jung E, Chaiworapongsa T, Gudicha DW, Suksai M, Gallo DM, Chaemsaithong P, Bosco M, Al Qasem M, Than NG et al. Perturbations in the kinetics of the thrombin generation assay identify women at risk for preeclampsia in the first trimester and provide a rationale for a preventive approach. Am J Obstet Gynecol. 2022;S0002-9378(22)02164-0.

 

Gomez-Tolub R, Rabinovich A, Kachko E, Benshalom-Tirosh N, Tirosh D, Thachil J, Besser L, Than NG, Erez O. Placental abruption as a trigger of DIC in women with HELLP syndrome: a population-based study. J Matern Fetal Neonatal Med. 2022;35:3259–3269.

 

Tarca AL, Taran A, Romero R, Jung E, Paredes C, Bhatti G, Ghita C, Chaiworapongsa T, Than NG, Hsu C-D. Prediction of preeclampsia throughout gestation with maternal characteristics and biophysical and biochemical markers: a longitudinal study. Am J Obstet Gynecol. 2022;226:126.e1-126.e22.

 

Oravecz O, Balogh A, Romero R, Xu Y, Juhasz K, Gelencser Z, Xu Z, Bhatti G, Pique-Regi R, Peterfia B, Than NG et al. Proteoglycans: Systems-Level Insight into Their Expression in Healthy and Diseased Placentas. Int J Mol Sci. 2022;23:5798.

 

Kalló G, Kumar A, Tőzsér J, Csősz É. Chemical Barrier Proteins in Human Body Fluids. Biomedicines. 2022;10:1472.

 

Kassay N, Toldi V, Tőzsér J, Szabó A. Cigarette smoke toxin hydroquinone and misfolding pancreatic lipase variant cooperatively promote endoplasmic reticulum stress and cell death. PLoS One. 2022;17:e0269936.

 

Mótyán JA, Kassay N, Matúz K, Tőzsér J. Different Mutation Tolerance of Lentiviral (HIV-1) and Deltaretroviral (BLV and HTLV) Protease Precursors. Viruses. 2022;14:1888.

 

Miltner N, Linkner TR, Ambrus V, Al-Muffti AS, Ahmad H, Mótyán JA, Benkő S, Tőzsér J, Mahdi M. Early suppression of antiviral host response and protocadherins by SARS-CoV-2 Spike protein in THP-1-derived macrophage-like cells. Front Immunol. 2022;13:999233.

 

Guba A, Bába O, Tőzsér J, Csősz É, Kalló G. Fast and Sensitive Quantification of AccQ-Tag Derivatized Amino Acids and Biogenic Amines by UHPLC-UV Analysis from Complex Biological Samples. Metabolites. 2022;12:272.

 

Mótyán JA, Mahdi M, Hoffka G, Tőzsér J. Potential Resistance of SARS-CoV-2 Main Protease (Mpro) against Protease Inhibitors: Lessons Learned from HIV-1 Protease. Int J Mol Sci. 2022;23:3507.

 

Bakos É, Német O, Kucsma N, Tőkési N, Stieger B, Rushing E, Tőkés A-M, Kele P, Tusnády GE, Özvegy-Laczka C. Cloning and characterization of a novel functional organic anion transporting polypeptide 3A1 isoform highly expressed in the human brain and testis. Front Pharmacol. 2022;13:958023.

 

Zeke A, Takács T, Sok P, Németh K, Kirsch K, Egri P, Póti ÁL, Bento I, Tusnády GE, Reményi A. Structural insights into the pSer/pThr dependent regulation of the SHP2 tyrosine phosphatase in insulin and CD28 signaling. Nat Commun. 2022;13:5439.

 

Dobson L, Szekeres LI, Gerdán C, Langó T, Zeke A, Tusnády GE. TmAlphaFold database: membrane localization and evaluation of AlphaFold2 predicted alpha-helical transmembrane protein structures. Nucleic Acids Res. 2022;gkac928.

2021

Gonda X, Eszlari N, Torok D, Gal Z, Bokor J, Millinghoffer A, Baksa D, Petschner P, Antal P, Breen G, Juhasz G, Bagdy G. Genetic underpinnings of affective temperaments: a pilot GWAS investigation identifies a new genome-wide significant SNP for anxious temperament in ADGRB3 gene. Transl Psychiatry. 2021;11(1):337.

 

Lazary J, Eszlari N, Kriko E, Tozser D, Dome P, Deakin JFW, Juhasz G, Bagdy G. Genetic analyses of the endocannabinoid pathway in association with affective phenotypic variants. Neurosci Lett. 2021;744:135600.

 

Gargya, P., Bálint, B.L.: Histological Grade of Endometrioid Endometrial Cancer and Relapse Risk Can Be Predicted with Machine Learning from Gene Expression Data. Cancers, 2021; 13, 4348.

 

Bartha Á, Győrffy B. TNMplot.com: A Web Tool for the Comparison of Gene Expression in Normal, Tumor and Metastatic Tissues. Int J Mol Sci. 2021;22(5):2622

 

Pataki BA, Garriga J, Eritja R, Palmer JRB, Bartumeus F, Csabai I. Deep learning dentification for citizen science surveillance of tiger mosquitoes. Sci Rep. 2021;11(1):4718.

 

Pataki BA, Garriga J, Eritja R, Palmer JRB, Bartumeus F, Csabai I. Deep learning identification for citizen science surveillance of tiger mosquitoes. Sci Rep. 2021;11(1):4718.

 

Hernansaiz-Ballesteros RD, Földi C, Cardelli L, Nagy LG, Csikász-Nagy A. Evolution of opposing regulatory interactions underlies the emergence of eukaryotic cell cycle checkpoints. Sci Rep. 2021;11(1):11122.

 

Jenei A, Kalló G, Dajnoki Z, Gáspár K, Szegedi A, Kapitány A, Csősz É. Detection of Antimicrobial Peptides in Stratum Corneum by Mass Spectrometry. Int J Mol Sci. 2021;22(8):4233.

 

Erdős G, Pajkos M, Dosztányi Z. IUPred3: prediction of protein disorder enhanced with unambiguous experimental annotation and visualization of evolutionary conservation. Nucleic Acids Res. 2021;49(W1):W297-W303.

 

Mészáros B, Hajdu-Soltész B, Zeke A, Dosztányi Z. Mutations of Intrinsically Disordered Protein Regions Can Drive Cancer but Lack Therapeutic Strategies. Biomolecules. 2021;11(3):381.

 

Gombos K, Gálik B, Kalács KI, Gödöny K, Várnagy Á, Alpár D, Bódis J, Gyenesei A, Kovács GL. NGS-Based Application for Routine Non-Invasive Pre-Implantation Genetic Assessment in IVF. Int J Mol Sci. 2021;22(5):2443.

 

Nagy Á, Pongor S, Győrffy B. Different mutations in SARS-CoV-2 associate with severe and mild outcome. Int J Antimicrob Agents. 2021;57(2):106272.

 

Nagy Á, Munkácsy G, Győrffy B. Pancancer survival analysis of cancer hallmark genes. Sci Rep. 2021 Mar 15;11(1):6047.

 

Liszkay G, Mátrai Z, Czirbesz K, Jani N, Bencze E, Kenessey I.: Predictive and Prognostic Value of BRAF and NRAS Mutation of 159 Sentinel Lymph Node Cases in Melanoma-A Retrospective Single-Institute Study. Cancers (Basel). 2021

 

Patyi G, Hódi B, Solymosi D, Vass I, Kós PB. Increased sensitivity of heavy metal bioreporters in transporter deficient Synechocystis PCC6803 mutants. PLoS One. 2021;16(12):e0261135.

 

Menyhart O, Weltz B, Győrffy B. MultipleTesting.com: A tool for life science researchers for multiple hypothesis testing correction, PLoS One. 2021;16(6):e0245824.

 

Fekete F, Mangó K, Déri M, Incze E, Minus A, Monostory K. Impact of genetic and non-genetic factors on hepatic CYP2C9 expression and activity in Hungarian subjects. Sci Rep. 2021;11(1):17081.

 

Bányai L, Trexler M, Kerekes K, Csuka O, Patthy L. Use of signals of positive and negative selection to distinguish cancer genes and passenger genes. Elife. 2021;10:e59629.

 

Moreno-Indias I, Lahti L, Nedyalkova M, Elbere I, Roshchupkin G, Adilovic M, Aydemir O, Bakir-Gungor B, Pongor S, Claesson MJ és mtsai.  Statistical and Machine Learning Techniques in Human Microbiome Studies: Contemporary Challenges and Solutions, Front Microbiol. 2021;12:635781.

 

Magyar C, Mentes A, Cserző M, Simon I. Origin of Increased Solvent Accessibility of Peptide Bonds in Mutual Synergetic Folding Proteins. Int J Mol Sci. 2021;22(24):13404.

 

Szatmári L, Cserkész T, Laczkó L, Lanszki J, Pertoldi C, Abramov AV, Elmeros M, Ottlecz B, Hegyeli Z, Sramkó G. A comparison of microsatellites and genome-wide SNPs for the detection of admixture brings the first molecular evidence for hybridization between Mustela eversmanii and M. putorius (Mustelidae, Carnivora). Evol Appl. 2021;14(9):2286-2304.

 

Zeke A, Dobson L, Szekeres LI, Langó T, Tusnády GE. PolarProtDb: A Database of Transmembrane and Secreted Proteins showing Apical-Basal Polarity. J Mol Biol. 2021;433(11):166705.

 

Dobson L, Tusnády GE. MemDis: Predicting Disordered Regions in Transmembrane Proteins. Int J Mol Sci. 2021;22(22):12270.